Immune Life

身体如何合成GSH

谷胱甘肽主要在细胞内通过两个酶促步骤合成。

Step 1: cysteine joins glutamate

The enzyme glutamate-cysteine ligase combines glutamate and cysteine. This is the rate-limiting step and is strongly affected by cysteine availability.

Step 2: glycine completes the molecule

Glutathione synthetase adds glycine, forming glutathione. Cells then use and recycle GSH continuously according to demand.

Cystine delivery

Cystine consists of two cysteine molecules connected by a disulfide bond. Cells can transport cystine and reduce it to cysteine for use in glutathione production. The details vary by tissue and transport system.

获取可信的健康科普

仅供健康科普，不构成医疗建议。